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Prokaryotic gene expression / edited by Simon Baumberg

Published
Oxford ; New York : Oxford University Press, 1999.
Physical Description
1 online resource (xx, 325 pages) : illustrations
Additional Creators
Baumberg, S.
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Contents
History and overview / Simon Baumberg -- Protein recognition of specific DNA and RNA binding sites / Peter G. Stockley -- Promoters, sigma factors, and variant RNA polymerases / John D. Helmann -- Repressors and activators / Stephen J.W. Busby -- Post-transcriptional control / Zhiping Gu and Paul S. Lovett -- Prokaryotic DNA topology and gene expression / Karl Drlica, Erden-Dalai Wu, Chang-Rung Chen, Jian-Ying Wang, Xilin Zhao, Chen Xu, Lin Qiu, Muhammad Malik, Samuel Kayman, and S. Marvin Friedman -- Integration of control devices: a global regulatory network in Escherichia coli / Regine Hengge-Aronis -- Two-component systems / Mariette R. Atkinson and Alexander J. Ninfa -- Switch systems / J.R. Saunders -- Integration of control devices: pathogenicity / Charles J. Dorman -- Integration of control devices: sporulation and antibiotic production / Michael D. Yudkin and Keith F. Chater -- Evolution of prokaryotic regulatory systems / Simon Baumberg.
Summary
Prokaryotic gene expression is not only of theoretical interest but also of highly practical significance. It has implications for other biological problems, such as developmental biology and cancer, brings insights into genetic engineering and expression systems, and has consequences for important aspects of applied research. For example, the molecular basis of bacterial pathogenicity has implications for new antibiotics and in crop development. Prokaryotic Gene; Expression is a major review of the subject, providing up-to-date coverage as well as numerous insights by the prestigious authors. Topics covered include operons; protein recognition of sequence specific DNA- and RNA-binding sites; promoters; sigma factors, and variant tRNA polymerases; repressors and activators;; post-transcriptional control and attenuation; ribonuclease activity, mRNA stability, and translational repression; prokaryotic DNA topology, topoisomerases, and gene expression; regulatory networks, regulatory cascades and signal transduction; phosphotransfer reactions; switch systems, transcriptional and translational modulation, methylation, and recombination mechanisms; pathogenicity, toxin regulation and virulence determinants; sporulation and genetic regulation of antibiotic production;; origins of regulatory molecules, selective pressures and evolution of prokaryotic regulatory mechanisms systems. Over 1100 references to the primary literature are cited. Prokaryotic Gene Expression is a comprehensive and authoritative review of current knowledge and research in the area. It is; essential reading for postgraduates and researchers in the field. Advanced undergraduates in biochemistry, molecular biology, and microbiology will also find this book useful.
Subject(s)
ISBN
0585483418 (electronic bk.)
9780585483412 (electronic bk.)
128037540X
9781280375408
9786610375400
6610375402
0199636044 (hardbound)
9780199636044 (hardbound)
0199636036 (pbk.)
9780199636037 (pbk.)
Bibliography Note
Includes bibliographical references and index.
View MARC record | catkey: 43316441