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Principles and practice of clinical electrophysiology of vision / editors, John R. Heckenlively and Geoffrey B. Arden ; associate editors, Steven Nusinowitz, Graham E. Holder, Michael Bach

Published
Cambridge, Mass. : MIT Press, [2006]
Copyright Date
©2006
Edition
2nd ed.
Physical Description
1 online resource (xxii, 977 pages, 32 unnumbered pages of plates) : illustrations (some color)
Additional Creators
Heckenlively, John R. and Arden, Geoffrey B. (Geoffrey Bernard)
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Language Note
English.
Contents
1 History of the electroretinogram -- 2 History of electro-oculography -- 3 History of visual evoked cortical testing -- 4 The photoreceptor-retinal pigment epithelium interface -- 5 Membrane mechanisms of the retinal pigment epithelium -- 6 Functional organization of the retina -- 7 Phototransduction and photoreceptor physiology -- 8 Synaptic transmission: sensitivity control mechanisms -- 9 Structure and function of retinal synapses: role of cell adhesion molecules and extracellular matrix -- 10 Central disorders of vision in humans -- 11 Origin and significance of the electro-oculogram -- 12 Origin of the electroretinogram -- 13 Origin of the pattern electroretinogram -- 14 Multifocal electroretinographic and visual evoked potential techniques -- 15 Origin of the visual evoked potentials -- 16 Data acquisition systems for electrodiagnostic testing -- 17 Electrodes for visual testing -- 18 Amplifiers and special-purpose data acquisition systems -- 19 Stimulus devices, calibration, and measurement of light -- 20 Introduction to the ISCEV standards -- EOG standard -- Standard for clinical electroretinography -- Visual evoked potentials standard -- Guidelines for basic multifocal electroretinography -- 21 Multifocal techniques -- 22 Pattern electroretinogram -- 23 Assessing infant acuity, fusion, and stereopsis with visual evoked potentials -- 24 Aging and pattern visual evoked cortical potential -- 25 Aberrant albino and achiasmat visual pathways: noninvasive electrophysiological assessment -- 26 Clinical psychophysical techniques -- 27 Measurement of contrast sensitivity -- 28 Suppressive rod-cone interaction -- 29 Use of fluorescein angiography as an adjunct to electrophysiological testing -- 30 Experimental design and data analyses in vision function testing -- 31 Analytical techniques -- 32 Reverse correlation methods -- 33 Stimulus-response functions for the scotopic b-wave -- 34 Kernel analysis -- 35 Measuring the health of the human photoreceptors with the leading edge of the a-wave -- 36 Localizing lesions in the visual system -- 37 Paired-flash ERG analysis of rod phototransduction and adaptation -- 38 Hyperabnormal (supranormal) electroretinographic responses -- 39 Technical issues in evaluating patients for therapeutic trials. and 40 Early receptor potential -- 41 Nonphotic standing potential responses: hyperosmolarity, bicarbonate, and diamox responses -- 42 Direct current electroretinogram -- 43 Oscillatory potentials of the electroretinogram -- 44 Flicker electroretinography -- 45 Chromatic recordings of electroretinograms -- 46 Adaptation effects on the electroretinogram -- 47 Clinical electrophysiological and psychophysical investigations into color defects -- 48 Causes and cures of artifacts -- 49 Testing levels of the visual system -- 50 Effects of high myopia on the electroretinogram -- 51 Electrodiagnostic testing in malingering and hysteria -- 52 Developmental amblyopia -- 53 Visual evoked potentials in cortical blindness -- 54 Drug side effects and toxicology of the visual system -- 55 Mitochondrial diseases -- 56 Diseases of the middle retina: venous and arterial occlusions -- 57 Acute disorders of the outer retina, pigment epithelium and choroid -- 58 Autoimmune retinopathy, CAR and MAR syndromes -- 59 Ischemic optic neuropathy -- 60 Gyrate atrophy of the choroid and retina -- 61 Dominant drusen -- 62 Stargardt disease -- 63 Bietti's crystalline dystrophy of the cornea and retina -- 64 Lever congenital amaurosis -- 65 Pattern dystrophies -- 66 Best vitelliform macular dystrophy -- 67 Sorsby's fundus dystrophy -- 68 Choroideremia -- 69 Retinitis pigmentosa -- 70 Cone dystrophies and degenerations -- 71 Vitamin A deficiency -- 72 Differential diagnosis of the electronegative electroretinogram -- 73 Juvenile x-linked retinoschisis -- 74 Congenital stationary night blindness -- 75 Quinine retinopathy -- 76 Leber's hereditary optic neuropathy -- 77 Pattern electroretinogram in glaucoma and ocular hypertension -- 78 Chiasmal and retrochiasmal lesions -- 79 Optic nerve and central nervous dysfunctions: Parkinson's disease and multiple sclerosis -- 80 r Diseases of fatty acid storage and metabolism: neuronal ceroid lipofuscinoses and the long-chain 3-Hydroxyacyl-CoA dehydrogenase deficiency -- 81 Evaluating retinal function in the mouse retina with the electroretinogram -- 82 Electroretinograms of dog and chicken -- 83 Electroretinographic testing in larger animals -- 84 Visual evoked potentials in animals.
Summary
The long-awaited second edition of an authoritative reference on electrophysiologic vision testing, including detailed information on techniques and problems, basic physiology and anatomy, theoretical concepts, and clinical findings; with extensive new material. This authoritative text is the only comprehensive reference available on electrophysiologic vision testing, offering both practical information on techniques and problems as well as basic physiology and anatomy, theoretical concepts, and clinical correlations. The second edition, of the widely used text, offers extensive new material and updated information: 65 of the 84 chapters are completely new, with the changes reflecting recent advances in the field. The book will continue to be an essential resource for practitioners and scholars from a range of disciplines within vision science. The contributions not only cover new information--important material that is likely to become more important in the next decade--but also offer a long-range perspective on the field and its remarkable development in the last century. After discussing the history and background of clinical electrophysiology, the book introduces the anatomy of the retina and principles of cell biology in the visual pathways at the molecular, physiological, and biochemical levels. It relates these new findings to the techniques and interpretations of clinical tests, including the electro-oculogram (EOG), electroretinogram (ERG), and visual evoked potentials (VEP), which are discussed in detail, as are equipment, data acquisition and analysis, principles and protocols for clinical testing, diseases and dysfunction, and animal testing. Notable additions for this edition include chapters on the origin of electroretinogram waveforms, multifocal techniques, testing in standard laboratory animals, recent advances in analysis of abnormalities in disease, and the applications of these techniques to the study of genetic abnormalities.
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ISBN
9780262275187 (electronic bk.)
026227518X (electronic bk.)
0262083469
9780262083461
1423784154
9781423784159
0262311550
9780262311557
1282098225
9781282098220
9786612098222
6612098228
Digital File Characteristics
data file
Bibliography Note
Includes bibliographical references and index.
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