Affinity and efficacy : the components of drug-receptor interactions / Frederick J. Ehlert
- Author
- Ehlert, Frederick J.
- Additional Titles
- Components of drug-receptor interactions
- Published
- New Jersey : World Scientific, [2014]
- Physical Description
- 1 online resource
Access Online
- Contents
- Ligand-gated ion channels -- Affinity and efficacy of orthosteric ligands at ligand-gated ion channels -- Competitive interactions between orthostheric ligands at ligand-gated ion channels -- Analysis of allosteric interactions at ligand-gated ion channels -- G protein-coupled receptors and G protein signaling -- Affinity and efficacy of the agonist-receptor-G-protein interaction -- Estimating affinity and efficacy by reverse-engineering and response-clamp analysis -- Analysis of agonism and inverse agonism in signaling pathways that exhibit constitutive activity -- Analysis of ligand bias in receptor signaling through different G protein pathways -- Competitive interactions between orthosteric ligands in functional assays on G protein-coupled receptors -- Analysis of allosterism in functional assays on G protein-coupled receptors -- Analysis of drug-receptor interactions using radioligand binding assays on G protein-coupled receptors.
- Subject(s)
- Drug receptors
- Drugs—Effectiveness
- Drug-nutrient interactions
- Pharmaceutical chemistry
- Carrier proteins
- Radioligand assay
- Receptors, Drug
- Food-Drug Interactions
- Chemistry, Pharmaceutical
- Ligand-Gated Ion Channels
- Carrier Proteins
- Radioligand Assay
- Receptors, G-Protein-Coupled
- Récepteurs de médicaments
- Médicaments—Efficacité
- Interactions médicaments-aliments
- Chimie pharmaceutique
- Protéines de liaison
- Dosage radiocompétitif
- MEDICAL—Pharmacology
- ISBN
- 9789814324229 (electronic bk.)
9814324221 (electronic bk.)
9789814322560
9814322563 - Bibliography Note
- Includes bibliographical references.
View MARC record | catkey: 43638811