Horizons in cancer research. Volume 62 / Hiroto S. Watanabe, editor
- Published
- New York : Nova Biomedical, [2016]
- Physical Description
- 1 online resource
- Additional Creators
- Watanabe, Hiroto S.
Access Online
- Series
- Contents
- Preface; Chapter 1; Epigenetic Regulation in Osteosarcoma; Abstract; Introduction; Epigenetic Regulatory Mechanisms; DNA Methylation; Histone Modifications; Epigenetic Alterations in Osteosarcoma; The Rb Pathway; The p53 Pathway; MicroRNAs; Monomethyl Histone H3 Lysine 27; Epigenetically Targeted Therapies; DNA Demethylating Agents; Histone Modification Agents; Combination Therapy; Clinical Trials; Future Treatment Directions and Precision Therapy; Conclusion; References; Chapter 2; Osteosarcoma Cell Functions: Focus on Extracellular Matrix Signaling; Abstract; Introduction, Osteoid/Bone CellsOsteosarcoma; Extracellular Matrices; Osteosarcoma and Extracellular Matrix; Small Leucine-Rich Repeat Proteoglycans (SLRPs); Syndecans and Versican; Matrix Metallo-Proteinases (MMPs); Collagen; Hyaluronan; ECM Mediators; PTH Signaling and Osteosarcoma; Conclusion; References; Chapter 3; The Long-Term Effects of Ultraviolet Radiation: Photocarcinogenesis; Abstract; Part I; Acute Effects of UVR; Spectrum of UVR; Clinical Changes Following UVR Exposure; Histological and Molecular Changes Following UVR Exposure; Changes in DNA Occuring After UVR Exposure, General Adaptive Mechanisms Protecting against UVRApoptosis and DNA Repair Mechanisms; UVR and Immunomodulation; Part II -- Photocarcinogenesis; UVR as a Carcinogen; Theory of Photocarcinogenesis; Initiation Phase of Photocarcinogenesis; Promotion Phase of Photocarcinogenesis; Additional Mechanisms Implicated in Photocarcinogenesis; Conclusion; References; Chapter 4; Skin Cancer and Sunscreen Use: Psychological Factors; Abstract; Introduction; Who Is at Risk for Skin Cancer?; How to Reduce Risk of Skin Cancer; Levels of Appropriate Sunscreen Use; Sunscreen use and Education, Psychological FactorsBackground Influencing Factors; Past Behaviour; Demographics and Culture; Gender; Age; Education; Cultural Factors; Stereotypes and Stigma; Personality, Mood and Emotions; Perceived Risk; Susceptibility; Severity; Media Exposure; Attitudes towards Sunscreen Use; Norms; Self-Efficacy; Intentions; Interventions and Psychological Theory; Information and Communication Technology; Conclusion; References; Biographical Sketch; Chapter 5; Involvement of Treg Cells and TGFB in HPV Infection and Cervical Cancer Development; Abstract; 1. Introduction; 2. HPV; 3. Regulatory T Cells, and 4. Transforming Growth Factor Beta (TFGB)5. New Insights of TGFB in Cervical Cancer; 6. Tregs and HPV: Tregs as Prognostic Marker in HPV Related Cancer; Conclusion; References; Chapter 6; American Cranberry (Vaccinium macrocarpon) Extract Affects Expression of Insulin-Like Growth Factor-I and Insulin-Like Growth Factor Binding Proteins in Human Prostate Cancer Cells In Vitro; Abstract; Introduction; Materials and Methods; Materials; Preparation of Cranberry Extract; Cell Culture and Treatment with Whole Cranberry Extract; Immunoblot Analysis; Statistical Analysis; Results
- Subject(s)
- ISBN
- 9781634854634
9781634854801 (electronic bk.)
1634854802 (electronic bk.) - Bibliography Note
- Includes bibliographical references and index.
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