A historic perspective on multiple sclerosis / Dolores González-Morón and Pablo Villoslada -- Bacterial role in the development of chronic multiple sclerosis / Alan Ebringer and Taha Rashid -- Animal models of multiple sclerosis / Beatriz Moreno and Pablo Villoslada -- Immunopathology and immuumunomodulation in experimental autoimmune encephalomyelitis and multiple sclerosis / R. Coveñas ... [and others] -- Indirect visualization of specified antigenic modifications induced by nitric oxide in an experimental model of allergic encephalomyelitis / D. Bodet ... [and others] -- A new paradigm for multiple sclerosis / Michel Geffard... [and others].