Proton microprobe analysis of zinc in skeletal tissues. [Proton induced x-ray emission analysis].

Author: Doty, S. B.
Published: United States : [publisher not identified], 1980.
Springfield, Va. : National Technical Information Service, [approximately 1980]
Physical Description: microfiche : negative ; 11 x 15 cm
Additional Creators: Hanson, A. L., Jones, K. W., Kraner, H. W., and Shroy, R. E.

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Summary

A proton microprobe with windowless exit port was used to study zinc distributions in various types of skeletal tissues. The use of an external beam facilitated positioning of the targets for examination of particular points of interest. The proton microprobe is uniquely suited to this work since it combines high sensitivity for zinc determinations in thick samples with good spatial resolution. Measurements on rat and rabbit Achilles tendon showed a significant increase in zinc concentrations as the beam moved from the unmineralized collagen into the mineralized attachment site. Cartilage gave a similar result, with calcified cartilage having a greater zinc level than the articular surface on unmineralized epiphyseal cartilage.

Report Numbers

BNL-27914; CONF-800677-1

Other Subject(s)

Collection

NTIS collection.

Note

DOE contract number: AC02-76CH00016
OSTI Identifier 5344752
Research organization: Brookhaven National Lab., Upton, NY (USA).
Research organization: Columbia Univ., New York (USA).

Funding Information