Actions for Fatty acid transport into the brain

Email RIS file
Bookmark
Report an Issue

Fatty acid transport into the brain

Author
Dhopeshwarkar, G. A.
Published
United States : [publisher not identified], [date of publication not identified]
[Oak Ridge, Tennessee] : [U.S. Atomic Energy Commission], [date of publication not identified]
Physical Description
microfiche : negative ; 11 x 15 cm
Additional Creators
McConnell, D. H., Mead, J. F., and Subramanian, C.

Availability

I Want It
I Want It

Finding items...

Summary
Fifteen ..mu..c of 1-/sup 14/C palmitate was injected into three groups of rats. Group I served as control animals, group II animals were subjected to functional hepatectomy, and group III animals received the tracer by an intracarotid injection followed by decapitation fifteen seconds later. The circulating blood lipids in the control group had most of the radioactivity in the triglyceride fraction whereas in both hepatectomized and carotid injected rats the blood free fatty acid (FFA) fraction had most of the radioactivity. Under these conditions the uptake of radioactivity by the brain was about six times higher in hepatectomized animals and fourteen times higher in the intracarotid injected animals than in the control group. This indicates that FFA is a preferred form of fatty acid transport to the brain.
Report Numbers
UCLA-12-839
Other Subject(s)
Collection
U.S. Atomic Energy Commission depository collection.
Note
DOE contract number: AC03-76SF00012
OSTI Identifier 6665733
Research organization: California Univ., Los Angeles (USA). Lab. of Nuclear Medicine and Radiation Biology.
View MARC record | catkey: 47046533