The diagnostics required for studying the disassembly of isochorically heated liquids are assessed. This treatment covers the measurement of energy deposition in the liquid and the evaluation of the resulting disassembly. Both optical and ultrasonic methods are feasible for determining the uniformity of energy deposition. Penetrating radiation methods are most suitable for evaluating the early stages of disassembly whether the chosen liquid is optically transparent or opaque. In the advanced stages of disassembly, a variety of optical methods, including high-speed framing and ensemble Mie scattering, offer significant advantages in resolution and the capability to observe the complete event. The diagnostics covered in this report range from state-of-the-art commercially available instrumentation to advanced methods appearing in the literature.