Pt. I. Differentiating Characteristics of Vaccines -- 1. Envisaging and Developing a Vaccine -- 2. Planning for Vaccine Launch -- 3. Rolling Out the New Vaccine -- Pt. II. Four Case Studies -- 4. Diphtheria, Tetanus, and Pertussis and Related Combination Vaccines -- 5. Seasonal Influenza Vaccines -- 6. Prevnar - The Seven-Valent Pneumococcal Conjugate Vaccine -- 7. Varicella Zoster Vaccines -- Pt. III. Ongoing and Future Issues in Vaccine Policies and R&D -- 8. Challenges in Maintaining Public Trust in Vaccine Safety -- Conclusion: Beyond the Turning Point-The Expanding Focus of Vaccine R&D -- App. A. Organizations (And Number of Individuals) Interviewed, February-August 2007 -- App. B. The Three Traditional Phases of Clinical Development for Vaccines: A Summary -- App. C. Advisory Committee on Immunization Practices Recommended Immunization Schedules, 2009 -- App. D. Cdc Pediatric, Adult, and Influenza Vaccine Price Lists, 2008.