Animal models in cardiovascular research [electronic resource] / David R. Gross
- Gross, David R. (David Ross)
- Dordrecht ; New York : Springer, 
- Copyright Date:
- 3rd ed.
- Physical Description:
- 1 online resource (xxv, 431 pages) : illustrations
- General principles of animal selection and normal physiological values -- Preanesthesia, anesthesia, chemical restraint, and the recognition and treatment of pain and distress -- Normal cardiac function parameters -- Measuring cardiac function -- Measuring vascular function and ventricular/arterial coupling dynamics -- Isolated heart preparations, problems, and pitfalls -- Cardiovascular effects of anesthetics, sedatives, postoperative analgesic agents, and other pharmaceuticals -- Naturally occurring and iatrogenic animal models of valvular, infectious, and arrhythmic cardiovascular disease -- Iatrogenic models of ischemic heart disease -- Iatrogenic, transgenic, and naturally occurring models of cardiomyopathy and heart failure -- Iatrogenic, congenic, and transgenic models of hypertension -- Naturally occurring, iatrogenic and transgenic models of atherosclerotic disease -- Animal models for the study of neurohumeral and central neural control of the cardiovascular system -- Other transgenic animal models used in cardiovascular studies.
- This new edition of "Animal Models in Cardiovascular Research" describes historical and recent advances in our understanding of the cardiovascular system from studies conducted in a variety of animal models. Since the last edition we have witnessed an explosion in the use of both congenic and transgenic animals. The use of specific knock-in and knock-out transgenic models has resulted in an avalanche of genetic, molecular and protein-based information that, potentially, could result in an amazing new array of treatment and management options. However, the results of these studies als.
- 9780387959627 (e-isbn)
- AVAILABLE ONLINE TO AUTHORIZED PSU USERS.
- Bibliography Note:
- Includes bibliographical references and index.
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