Molecularly targeted therapy for childhood cancer [electronic resource] / Peter J. Houghton, Robert J. Arceci, editors
- New York : Springer, 
- Copyright Date:
- Physical Description:
- 1 online resource (xviii, 536 pages) : illustrations (some color)
- Additional Creators:
- Houghton, Peter J. and Arceci, Robert
- SpringerLink: ezaccess.libraries.psu.edu
- The Emerging Era of Targeted Therapy in Childhood Acute Lymphoblastic Leukemia; Molecular Targeted Therapies in T-CellAcute Lymphoblastic Leukemia; Molecularly Targeted Therapy for Infant ALL; Targeted Therapeutic Approaches for AML; Acute Promyelocytic Leukaemia; Down Syndrome and Acute Myeloid Leukemia: An Unique Genetic Sensitivity to Chemotherapy; Targeting RAS Signaling Pathways in Juvenile Myelomonocytic Leukemia (JMML); Chronic Myeloid Leukemia: Pathophysiology and Therapeutics; Molecularly Targeted Therapies in Pediatric Myelodysplastic Syndromes.
- Each chapter will focus on the known molecular characteristics of specific childhood cancers, focusing on how the molecular 'drivers' can be exploited from a therapeutic standpoint with currently available targeted agents. Where applicable, integration of targeted therapies with conventional cytotoxic agents will be considered. This volume will provide a comprehensive summary of molecular characteristics of childhood cancers, and how the changes involved in transformation provide us with opportunities for developing relatively less toxic, but curative, therapies.
- AVAILABLE ONLINE TO AUTHORIZED PSU USERS.
- Bibliography Note:
- Includes bibliographical references and index.
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