Actions for Vander's human physiology : the mechanisms of body function
Vander's human physiology : the mechanisms of body function / Eric P. Widmaier, Hershel Raff, Kevin T. Strang
- Author
- Widmaier, Eric P.
- Additional Titles
- Human physiology
- Published
- New York : McGraw-Hill, [2011]
- Copyright Date
- ©2011
- Edition
- 12th ed. / Eric P. Widmaier, Hershel Raff, Kevin T. Strang.
- Physical Description
- 1 volume (various pagings) : illustrations (chiefly color) ; 29 cm
- Additional Creators
- Raff, Hershel, 1953-, Strang, Kevin T., and Vander, Arthur J., 1933-
- Contents
- Machine generated contents note: ch. 1 Homeostasis: A Framework for Human Physiology -- 1.1.The Scope of Human Physiology -- 1.2.How Is the Body Organized? -- Muscle Cells and Tissue -- Neurons and Nervous Tissue -- Epithelial Cells and Epithelial Tissue -- Connective-Tissue Cells and Connective Tissue -- Organs and Organ Systems -- 1.3.Body Fluid Compartments -- 1.4.Homeostasis: A Defining Feature of Physiology -- 1.5.General Characteristics of Homeostatic Control Systems -- Feedback Systems -- Resetting of Set Points -- Feedforward Regulation -- 1.6.Components of Homeostatic Control Systems -- Reflexes -- Local Homeostatic Responses -- 1.7.Intercellular Chemical Messengers -- 1.8.Processes Related to Homeostasis -- Adaptation and Acclimatization -- Biological Rhythms -- Balance in the Homeostasis of Chemical Substances in the Body -- ch. 1 Clinical Case Study -- Test Questions -- Quantitative and Thought Questions -- Answers to Physiological Inquiries -- ch. 2 Chemical Composition of the Body -- 2.1.Atoms -- Components of Atoms -- Atomic Number -- Atomic Weight -- Ions -- Atomic Composition of the Body -- 2.2.Molecules -- Covalent Chemical Bonds -- Hydrogen Bonds -- Molecular Shape -- Ionic Molecules -- Free Radicals -- 2.3.Solutions -- Water -- Molecular Solubility -- Concentration -- Hydrogen Ions and Acidity -- 2.4.Classes of Organic Molecules -- Carbohydrates -- Lipids -- Proteins -- Nucleic Acids -- ATP -- ch. 2 Clinical Case Study -- Test Questions -- Answers to Physiological Inquiries -- ch. 3 Cellular Structure, Proteins, and Metabolism -- Section A Cell Structure -- 3A.1.Microscopic Observations of Cells -- 3A.2.Membranes -- Membrane Structure -- Membrane Junctions -- 3A.3.Cell Organelles -- Nucleus -- Ribosomes -- Endoplasmic Reticulum -- Golgi Apparatus -- Endosomes -- Mitochondria -- Lysosomes -- Peroxisomes -- Vaults -- Cytoskeleton -- Section B Proteins -- 3B.1.Genetic Code -- 3B.2.Protein Synthesis -- Transcription: mRNA Synthesis -- Translation: Polypeptide Synthesis -- Regulation of Protein Synthesis -- Mutation -- 3B.3.Protein Degradation -- 3B.4.Protein Secretion -- Section C Protein-Binding Sites -- 3C.1.Binding Site Characteristics -- Chemical Specificity -- Affinity -- Saturation -- Competition -- 3C.2.Regulation of Binding Site Characteristics -- Allosteric Modulation -- Covalent Modulation -- Section D Enzymes and Chemical Energy -- 3D.1.Chemical Reactions -- Determinants of Reaction Rates -- Reversible and Irreversible Reactions -- Law of Mass Action -- 3D.2.Enzymes -- Cofactors -- 3D.3.Regulation of Enzyme-Mediated Reactions -- Substrate Concentration -- Enzyme Concentration -- Enzyme Activity -- 3D.4.Multienzyme Reactions -- Section E Metabolic Pathways -- 3E.1.Cellular Energy Transfer -- Glycolysis -- Krebs Cycle -- Oxidative Phosphorylation -- 3E.2.Carbohydrate, Fat, and Protein Metabolism -- Carbohydrate Metabolism -- Fat Metabolism -- Protein and Amino Acid Metabolism -- Metabolism Summary -- 3E.3.Essential Nutrients -- Vitamins -- ch. 3 Clinical Case Study -- Test Questions -- Quantitative and Thought Questions -- Answers to Physiological Inquiries -- ch. 4 Movement of Molecules Across Cell Membranes -- 4.1.Diffusion -- Magnitude and Direction of Diffusion -- Diffusion Rate Versus Distance -- Diffusion Through Membranes -- 4.2.Mediated-Transport Systems -- Facilitated Diffusion -- Active Transport -- 4.3.Osmosis -- Extracellular Osmolarity and Cell Volume -- 4.4.Endocytosis and Exocytosis -- Endocytosis -- Exocytosis -- 4.5.Epithelial Transport -- ch. 4 Clinical Case Study -- Test Questions -- Quantitative and Thought Questions -- Answers to Physiological Inquiries -- ch. 5 Control of Cells by Chemical Messengers -- 5.1.Receptors -- Regulation of Receptors -- 5.2.Signal Transduction Pathways -- Pathways Initiated by Lipid-Soluble Messengers -- Pathways Initiated by Water-Soluble Messengers -- Plasma Membrane Receptors and Gene Transcription -- Cessation of Activity in Signal Transduction Pathways -- ch. 5 Clinical Case Study -- Test Questions -- Quantitative and Thought Questions -- Answers to Physiological Inquiries -- ch. 6 Neuronal Signaling and the Structure of the Nervous System -- Section A Neural Tissue -- 6A.1.Structure and Maintenance of Neurons -- 6A.2.Functional Classes of Neurons -- 6A.3.Glial Cells -- 6A.4.Neural Growth and Regeneration -- Section B Membrane Potentials -- 6B.1.Basic Principles of Electricity -- 6B.2.The Resting Membrane Potential -- 6B.3.Graded Potentials and Action Potentials -- Graded Potentials -- Action Potentials -- Section C Synapses -- 6C.1.Functional Anatomy of Synapses -- 6C.2.Mechanisms of Neurotransmitter Release -- 6C.3.Activation of the Postsynaptic Cell -- Excitatory Chemical Synapses -- Inhibitory Chemical Synapses -- 6C.4.Synaptic Integration -- 6C.5.Synaptic Strength -- Modification of Synaptic Transmission by Drugs and Disease -- 6C.6.Neurotransmitters and Neuromodulators -- Acetylcholine -- Biogenic Amines -- Amino Acid Neurotransmitters -- Neuropeptides -- Gases -- Purines -- 6C.7.Neuroeffector Communication -- Section D Structure of the Nervous System -- 6D.1.Central Nervous System: Brain -- Forebrain -- Cerebellum -- Brainstem -- 6D.2.Central Nervous System: Spinal Cord -- 6D.3.Peripheral Nervous System -- 6D.4.Autonomic Nervous System -- 6D.5.Blood Supply, Blood-Brain Barrier, and Cerebrospinal Fluid -- ch. 6 Clinical Case Study -- Test Questions -- Quantitative and Thought Questions -- Answers to Physiological Inquiries -- ch. 7 Sensory Physiology -- Section A General Principles -- 7A.1.Sensory Receptors -- The Receptor Potential -- 7A.2.Primary Sensory Coding -- Stimulus Type -- Stimulus Intensity -- Stimulus Location -- Central Control of Afferent Information -- 7A.3.Ascending Neural Pathways in Sensory Systems -- 7A.4.Association Cortex and Perceptual Processing -- Factors That Affect Perception -- Section B Specific Sensory Systems -- 7B.1.Somatic Sensation -- Touch and Pressure -- Sense of Posture and Movement -- Temperature -- Pain -- Neural Pathways of the Somatosensory System -- 7B.2.Vision -- Light -- Overview of Eye Anatomy -- The Optics of Vision -- Photoreceptor Cells and Phototransduction -- Neural Pathways of Vision -- Color Vision -- Color Blindness -- Eye Movement -- 7B.3.Hearing -- Sound -- Sound Transmission in the Ear -- Hair Cells of the Organ of Corti -- Neural Pathways in Hearing -- 7B.4.Vestibular System -- The Semicircular Canals -- The Utricle and Saccule -- Vestibular Information and Pathways -- 7B.5.Chemical Senses -- Taste -- Smell -- ch. 7 Clinical Case Study -- Test Questions -- Quantitative and Thought Questions -- Answers to Physiological Inquiries -- ch. 8 Consciousness, the Brain, and Behavior -- 8.1.States of Consciousness -- Electroencephalogram -- The Waking State -- Sleep -- Neural Substrates of States of Consciousness -- Coma and Brain Death -- 8.2.Conscious Experiences -- Selective Attention -- Neural Mechanisms of Conscious Experiences -- 8.3.Motivation and Emotion -- Motivation -- Emotion -- 8.4.Altered States of Consciousness -- Schizophrenia -- The Mood Disorders: Depressions and Bipolar Disorders -- Psychoactive Substances, Dependences, and Tolerance -- 8.5.Learning and Memory -- Memory -- The Neural Basis of Learning and Memory -- 8.6.Cerebral Dominance and Language -- ch. 8 Clinical Case Study -- Test Questions -- Quantitative and Thought Questions -- Answers to Physiological Inquiries -- ch. 9 Muscle -- Section A Skeletal Muscle -- 9A.1.Structure -- 9A.2.Molecular Mechanisms of Skeletal Muscle Contraction -- Sliding-Filament Mechanism -- Roles of Troponin, Tropomyosin, and Ca2+ in Contraction -- Excitation-Contraction Coupling -- Membrane Excitation: The Neuromuscular Junction -- 9A.3.Mechanics of Single-Fiber Contraction -- Twitch Contractions -- Load-Velocity Relation -- Frequency-Tension Relation -- Length-Tension Relation -- 9A.4.Skeletal Muscle Energy Metabolism -- Muscle Fatigue -- 9A.5.Types of Skeletal Muscle Fibers -- 9A.6.Whole-Muscle Contraction -- Control of Muscle Tension -- Control of Shortening Velocity -- Muscle Adaptation to Exercise -- Lever Action of Muscles and Bones -- 9A.7.Skeletal Muscle Disorders -- Muscle Cramps -- Hypocalcemic Tetany -- Muscular Dystrophy -- Myasthenia Gravis -- Section B Smooth and Cardiac Muscle -- 9B.1.Structure of Smooth Muscle -- 9B.2.Smooth Muscle Contraction and Its Control -- Cross-Bridge Activation -- Sources of Cytosolic Ca2+ -- Membrane Activation -- Types of Smooth Muscle -- 9B.3.Cardiac Muscle -- Cellular Structure of Cardiac Muscle -- Excitation-Contraction Coupling in Cardiac Muscle -- ch. 9 Clinical Case Study -- Test Questions -- Quantitative and Thought Questions -- Answers to Physiological Inquiries -- ch. 10 Control of Body Movement -- 10.1.Motor Control Hierarchy -- Voluntary and Involuntary Actions -- 10.2.Local Control of Motor Neurons -- Interneurons -- Local Afferent Input -- 10.3.The Brain Motor Centers and the Descending Pathways They Control -- Cerebral Cortex -- Subcortical and Brainstem Nuclei -- Cerebellum -- Descending Pathways -- 10.4.Muscle Tone -- Abnormal Muscle Tone -- 10.5.Maintenance of Upright Posture and Balance -- 10.6.Walking -- ch. 10 Clinical Case Study -- Test Questions -- Quantitative and Thought Questions -- Answers to Physiological Inquiries -- ch. 11 The Endocrine System -- Section A Principles of Hormonal Control Systems -- 11A.1.Hormone Structures and Synthesis -- Amine Hormones -- Peptide and Protein Hormones -- Steroid Hormones -- 11A.2.Hormone Transport in the Blood -- 11A.3.Hormone Metabolism and Excretion -- 11A.4.Mechanisms of Hormone Action -- Hormone Receptors -- Events Elicited by Hormone-Receptor Binding -- Pharmacological Effects of Hormones -- 11A.5.Inputs That Control Hormone Secretion -- Control by Plasma Concentrations of Mineral Ions or Organic Nutrients -- Control by Neurons -- Control by Other Hormones --, Contents note continued: 11A.6.Types of Endocrine Disorders -- Hyposecretion -- Hypersecretion -- Hyporesponsiveness and Hyperresponsiveness -- Section B The Hypothalamus and Pituitary Gland -- 11B.1.Control Systems Involving the Hypothalamus and Pituitary Gland -- Posterior Pituitary Gland Hormones -- Anterior Pituitary Gland Hormones and the Hypothalamus -- Section C The Thyroid Gland -- 11C.1.Synthesis of Thyroid Hormones -- 11C.2.Control of Thyroid Function -- 11C.3.Actions of Thyroid Hormones -- Metabolic Actions -- Permissive Actions -- Growth and Development -- 11C.4.Hypothyroidism and Hyperthyroidism -- Section D The Endocrine Response to Stress -- 11D.1.Physiological Functions of Cortisol -- 11D.2.Functions of Cortisol in Stress -- 11D.3.Adrenal Insufficiency and Cushing's Syndrome -- 11D.4.Other Hormones Released During Stress -- 11D.5.Psychological Stress and Disease -- Section E Endocrine Control of Growth -- 11E.1.Bone Growth -- 11E.2.Environmental Factors Influencing Growth -- 11E.3.Hormonal Influences on Growth -- Growth Hormone and Insulin-Like Growth Factors -- Thyroid Hormones -- Insulin -- Sex Hormones -- Cortisol -- Section F Endocrine Control of Ca2+ Homeostasis -- 11F.1.Effector Sites for Ca2+ Homeostasis -- Bone -- Kidneys -- Gastrointestinal Tract -- 11F.2.Hormonal Controls -- Parathyroid Hormone -- 1, 25-Dihydroxyvitamin D -- Calcitonin -- 11F.3.Metabolic Bone Diseases -- Hypercalcemia -- Hypocalcemia -- ch. 11 Clinical Case Study -- Test Questions -- Quantitative and Thought Questions -- Answers to Physiological Inquiries -- ch. 12 Cardiovascular Physiology -- Section A Overall Design of the Circulatory System -- 12A.1.System Overview -- 12A.2.Pressure, Flow, and Resistance -- Section B The Heart -- 12B.1.Anatomy -- Cardiac Muscle -- 12B.2.Heartbeat Coordination -- Sequence of Excitation -- Cardiac Action Potentials and Excitation of the SA Node -- The Electrocardiogram -- Excitation-Contraction Coupling -- Refractory Period of the Heart -- 12B.3.Mechanical Events of the Cardiac Cycle -- Mid-Diastole to Late Diastole -- Systole -- Early Diastole -- Pulmonary Circulation Pressures -- Heart Sounds -- 12B.4.The Cardiac Output -- Control of Heart Rate -- Control of Stroke Volume -- 12B.5.Measurement of Cardiac Function -- Section C The Vascular System -- 12C.1.Arteries -- Arterial Blood Pressure -- Measurement of Systemic Arterial Pressure -- 12C.2.Arterioles -- Local Controls -- Extrinsic Controls -- Endothelial Cells and Vascular Smooth Muscle -- Arteriolar Control in Specific Organs -- 12C.3.Capillaries -- Anatomy of the Capillary Network -- Velocity of Capillary Blood Flow -- Diffusion Across the Capillary Wall: Exchanges of Nutrients and Metabolic End Products -- Bulk Flow Across the Capillary Wall: Distribution of the Extracellular Fluid -- 12C.4.Veins -- Determinants of Venous Pressure -- 12C.5.The Lymphatic System -- Mechanism of Lymph Flow -- Section D Integration of Cardiovascular Function: Regulation of Systemic Arterial Pressure -- 12D.1.Baroreceptor Reflexes -- Arterial Baroreceptors -- The Medullary Cardiovascular Center -- Operation of the Arterial Baroreceptor Reflex -- Other Baroreceptors -- 12D.2.Blood Volume and Long-Term Regulation of Arterial Pressure -- 12D.3.Other Cardiovascular Reflexes and Responses -- Section E Cardiovascular Patterns in Health and Disease -- 12E.1.Hemorrhage and Other Causes of Hypotension -- Shock -- 12E.2.The Upright Posture -- 12E.3.Exercise -- Maximal Oxygen Consumption and Training -- 12E.4.Hypertension -- 12E.5.Heart Failure -- 12E.6.Hypertrophic Cardiomyopathy -- 12E.7.Coronary Artery Disease and Heart Attacks -- Section F Blood and Hemostasis -- 12F.1.Plasma -- 12F.2.The Blood Cells -- Erythrocytes -- Leukocytes -- Platelets -- Regulation of Blood Cell Production -- 12F.3.Hemostasis: The Prevention of Blood Loss -- Formation of a Platelet Plug -- Blood Coagulation: Clot Formation -- Anticlotting Systems -- Anticlotting Drugs -- ch. 12 Clinical Case Study -- Test Questions -- Quantitative and Thought Questions -- Answers to Physiological Inquiries -- ch. 13 Respiratory Physiology -- 13.1.Organization of the Respiratory System -- The Airways and Blood Vessels -- Site of Gas Exchange: The Alveoli -- Relation of the Lungs to the Thoracic (Chest) Wall -- 13.2.Ventilation and Lung Mechanics -- How is a Stable Balance Achieved Between Breaths? -- Inspiration -- Expiration -- Lung Compliance -- Airway Resistance -- Lung Volumes and Capacities -- Alveolar Ventilation -- 13.3.Exchange of Gases in Alveoli and Tissues -- Partial Pressures of Gases -- Alveolar Gas Pressures -- Gas Exchange Between Alveoli and Blood -- Matching of Ventilation and Blood Flow in Alveoli -- Gas Exchange Between Tissues and Blood -- 13.4.Transport of Oxygen in Blood -- What is the Effect of Po2 on Hemoglobin Saturation? -- Effects of Blood Pco2' H+ Concentration, Temperature, and DPG Concentration on Hemoglobin Saturation -- 13.5.Transport of Carbon Dioxide in Blood -- 13.6.Transport of Hydrogen Ion Between Tissues and Lungs -- 13.7.Control of Respiration -- Neural Generation of Rhythmic Breathing -- Control of Ventilation by Po2' Pco2, and H+ Concentration -- Control of Ventilation During Exercise -- Other Ventilatory Responses -- 13.8.Hypoxia -- Why Do Ventilation-Perfusion Abnormalities Affect O2 More Than CO2? -- Emphysema -- Acclimatization to High Altitude -- 13.9.Nonrespiratory Functions of the Lungs -- ch. 13 Clinical Cast Study -- Test Questions -- Quantitative and Thought Questions -- Answers to Physiological Inquiries -- ch. 14 The Kidneys and Regulation of Water and Inorganic Ions -- Section A Basic Principles of Renal Physiology -- 14A.1.Renal Functions -- 14A.2.Structure of the Kidneys and Urinary System -- 14A.3.Basic Renal Processes -- Glomerular Filtration -- Tubular Reabsorption -- Tubular Secretion -- Metabolism by the Tubules -- Regulation of Membrane Channels and Transporters -- "Division of Labor" in the Tubules -- 14A.4.The Concept of Renal Clearance -- 14A.5.Micturition -- Incontinence -- Section B Regulation of Ion and Water Balance -- 14B.1.Total-Body Balance of Sodium and Water -- 14B.2.Basic Renal Processes for Sodium and Water -- Primary Active Na+ Reabsorption -- Coupling of Water Reabsorption to Na+ Resbsorption -- Urine Concentration: The Countercurrent Multiplier System -- 14B.3.Renal Sodium Regulation -- Control of GFR -- Control of Na+ Reabsorption -- 14B.4.Renal Water Regulation -- Osmoreceptor Control of Vasopressin Secretion -- Baroreceptor Control of Vasopressin Secretion -- 14B.5.A Summary Example: The Response to Sweating -- 14B.6.Thirst and Salt Appetite -- 14B.7.Potassium Regulation -- Renal Regulation of K+ -- 14B.8.Renal Regulation of Calcium and Phosphate Ion -- 14B.9.Summary---Division of Labor -- 14B.10.Diuretics -- Section C Hydrogen Ion Regulation -- 14C.1.Sources of Hydrogen Ion Gain or Loss -- 14C.2.Buffering of Hydrogen Ion in the Body -- 14C.3.Integration of Homeostatic Controls -- 14C.4.Renal Mechanisms -- HCO3 - Handling -- Addition of New HCO3 - to the Plasma -- Renal Responses to Acidosis and Alkalosis -- 14C.5.Classification of Acidosis and Alkalosis -- ch. 14 Clinical Case Study -- Hemodialysis, Peritoneal Dialysis, and Transplantation -- Test Questions -- Quantitative and Thought Questions -- Answers to Physiological Inquiries -- ch. 15 The Digestion and Absorption of Food -- 15.1.Overview: Functions of the Gastrointestinal Organs -- 15.2.Structure of the Gastrointestinal Tract Wall -- 15.3.Digestion and Absorption -- Carbohydrate -- Protein -- Fat -- Vitamins -- Water and Minerals -- 15.4.How Are Gastrointestinal Processes Regulated? -- Basic Principles -- Mouth, Pharynx, and Esophagus -- Stomach -- Pancreatic Secretions -- Bile Secretion and Liver Function -- Small Intestine -- Large Intestine -- 15.5.Pathophysiology of the Gastrointestinal Tract -- Ulcers -- Vomiting -- Gallstones -- Lactose Intolerance -- Constipation and Diarrhea -- ch. 15 Clinical Case Study -- Test Questions -- Quantitative and Thought Questions -- Answers to Physiological Inquiries -- ch. 16 Regulation of Organic Metabolism and Energy Balance -- Section A Control and Integration of Carbohydrate, Protein, and Fat Metabolism -- 16A.1.Events of the Absorptive and Postabsorptive States -- Absorptive State -- Postabsorptive State -- 16A.2.Endocrine and Neural Control of the Absorptive and Postabsorptive States -- Insulin -- Glucagon -- Epinephrine and Sympathetic Nerves to Liver and Adipose Tissue -- Cortisol -- Growth Hormone -- Summary of Hormonal Controls -- Hypoglycemia -- 16A.3.Energy Homeostasis in Exercise and Stress -- Section B Regulation of Total-Body Energy Balance and Temperature -- 16B.1.Basic Concepts of Energy Expenditure -- Metabolic Rate -- 16B.2.Regulation of Total-Body Energy Stores -- Control of Food Intake -- Overweight and Obesity -- Eating Disorders: Anorexia Nervosa and Bulimia Nervosa -- What Should We Eat? -- 16B.3.Regulation of Body Temperature -- Mechanisms of Heat Loss or Gain -- Temperature-Regulating Reflexes -- Temperature Acclimatization -- 16B.4.Fever and Hyperthermia -- ch. 16 Clinical Case Study -- Test Questions -- Quantitative and Thought Questions -- Answers to Physiological Inquiries -- ch. 17 Reproduction -- Section A Overview of Terminology and General Principles -- Section B Gametogenesis, Sex Determination, and Sex Differentiation -- 17B.1.Gametogenesis -- 17B.2.Sex Determination -- 17B.3.Sex Differentiation -- Differentiation of the Gonads -- Differentiation of Internal and External Genitalia -- 17B.4.Sexual Differentiation of the Central Nervous System and Homosexuality -- Section C Male Reproductive Physiology -- 17C.1.Anatomy -- 17C.2.Spermatogenesis -- 17C.3.Transport of Sperm -- Erection -- Ejaculation -- 17C.4.Hormonal Control of Male Reproductive Functions -- Control of the Testes -- Testosterone -- 17C.5.Puberty -- Secondary Sex Characteristics and Growth -- Behavior --, and Contents note continued: 17C.6.Hypogonadism -- 17C.7.Andropause -- Section D Female Reproductive Physiology -- 17D.1.Anatomy -- 17D.2.Ovarian Functions -- Oogenesis -- Follicle Growth -- Formation of the Corpus Luteum -- Sites of Synthesis of Ovarian Hormones -- 17D.3.Control of Ovarian Function -- Follicle Development and Estrogen Synthesis During the Early and Middle Follicular Phases -- LH Surge and Ovulation -- The Luteal Phase -- 17D.4.Uterine Changes in the Menstrual Cycle -- 17D.5.Other Effects of Estrogen and Progesterone -- 17D.6.Androgens in Women -- 17D.7.Puberty -- 17D.8.Female Sexual Response -- 17D.9.Pregnancy -- Egg Transport -- Intercourse, Sperm Transport, and Capacitation -- Fertilization -- Early Development, Implantation, and Placentation -- Hormonal and Other Changes During Pregnancy -- Parturition -- Lactation -- Contraception -- Infertility -- 17D.10.Menopause -- ch. 17 Clinical Case Study -- Test Questions -- Quantitative and Thought Questions -- Answers to Physiological Inquiries -- ch. 18 The Immune System -- 18.1.Cells and Secretions Mediating Immune Defenses -- Immune Cells -- Cytokines -- 18.2.Innate Immune Responses -- Defenses at Body Surfaces -- Inflammation -- Interferons -- Toll-Like Receptors -- 18.3.Adaptive Immune Responses -- Overview -- Lymphoid Organs and Lymphocyte Origins -- Functions of B Cells and T Cells -- Lymphocyte Receptors -- Antigen Presentation to T Cells -- NK Cells -- Development of Immune Tolerance -- Antibody-Mediated Immune Responses: Defenses Against Bacteria, Extracellular Viruses, and Toxins -- Defenses Against Virus-Infected Cells and Cancer Cells -- 18.4.Systemic Manifestations of Infection -- 18.5.Factors That Alter the Resistance to Infection -- Acquired Immune Deficiency Syndrome (AIDS) -- Antibiotics -- 18.6.Harmful Immune Responses -- Graft Rejection -- Transfusion Reactions -- Allergy (Hypersensitivity) -- Autoimmune Disease -- Excessive Inflammatory Responses -- ch. 18 Clinical Case Study -- Test Questions -- Quantitative and Thought Questions -- Answers to Physiological Inquiries -- ch. 19 Medical Physiology: Integration Using Clinical Cases -- Case 19-1 A Woman with Palpitations and Heat Intolerance -- 19-1.1.Case Presentation -- 19-1.2.Physical Examination -- 19-1.3.Laboratory Tests -- 19-1.4.Diagnosis -- 19-1.5.Physiological Integration -- 19-1.6.Therapy -- Case 19-2 A Man with Chest Pain After a Long Airplane Flight -- 19-2.1.Case Presentation -- 19-2.2.Physical Examination -- 19-2.3.Laboratory Tests -- 19-2.4.Diagnosis -- 19-2.5.Physiological Integration -- 19-2.6.Therapy -- Case 19-3 A Man with Abdominal Pain, Fever, and Circulatory Failure -- 19-3.1.Case Presentation -- 19-3.2.Physical Examination -- 19-3.3.Laboratory Tests -- 19-3.4.Diagnosis -- 19-3.5.Physiological Integration -- 19-3.6.Therapy -- Case 19-4 A College Student with Nausea, Flushing, and Sweating -- 19-4.1.Case Presentation -- 19-4.2.Physical Examination -- 19-4.3.Laboratory Tests -- 19-4.4.Diagnosis -- 19-4.5.Physiological Integration -- 19-4.6.Therapy.
- Subject(s)
- ISBN
- 9780073378107 (hard copy : alk. paper)
0073378100 (hard copy : alk. paper)
9780077350017 (hbk.)
0077350014 (hbk.)
9780071222150 (pbk.)
0071222154 (pbk.) - Note
- Includes index.
- Source of Acquisition
- Fayette copy: Purchased with funds from the Paterno Libraries Endowment; 2010.
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