Biotechnology of plasma proteins / Roger L. Lundblad
- Author
- Lundblad, Roger L.
- Published
- Boca Raton, FL : CRC Press, [2013]
- Copyright Date
- ©2013
- Physical Description
- xiii, 446 pages : illustrations ; 24 cm.
- Series
- Contents
- Machine generated contents note: ch. 1 Blood, Plasma, Cells, and Other Biological Fluids -- ch. 2 Plasma Fractionation and Plasma Protein Products -- ch. 3 Methods for the Analysis of Plasma and Plasma Protein Fractions -- ch. 4 Albumin -- Structure of Albumin -- In Vitro Chemical Modification of Albumin -- Albumin as a Carrier -- Ligand-Binding by Albumin -- Purification and Characterization of HSA for Clinical Use -- Biological Activity of Albumin -- Enzymatic Activity of Albumin -- Clinical Use of Albumin -- Albumin as Diagnostic/Biomarker -- Pharmacokinetics of Albumin -- Analytical Methods for Albumin Including Use of Albumin as Standard for Analytical Methods -- Albumin as Excipient -- Conclusion -- References -- ch. 5 Plasma Immunoglobulins -- ch. 6 Factor VIII and von Willebrand Factor -- von Willebrand Factor -- Economic Issues Impacting the Hemophilia Business -- Conclusions and Future Directions -- References -- ch. 7 Plasma Proteinase Inhibitors -- Antithrombin -- α1-Antitrypsin (α1-Antiprotease Inhibitor, SERPINA1) -- Heparin Cofactor II (SERPIND1) -- α2-Macroglobulin -- Tissue Factor Pathway Inhibitor -- α2-Antiplasmin -- C1-Inhibitor (C1-Esterase Inhibitor) -- Plasminogen Activator Inhibitor-1 -- Protein C Inhibitor (Plasminogen Activator Inhibitor-3) -- References -- ch. 8 Vitamin K-Dependent Proteins -- ch. 9 Miscellaneous Plasma Proteins -- Fibrinogen -- Fibrin Sealant -- Autologous Fibrin Sealant -- Fibrinogen and Tissue Soldering -- Thrombin and Fibrin Foam -- Fibrinogen Plastics -- Thrombin -- Plasminogen and Plasmin -- Butyrylcholinesterase -- Fibronectin -- References.
- Summary
- "Discussing the role of plasma proteins in current biotechnology, this book describes the protein composition of human plasma, the fractionation of plasma to obtain therapeutic proteins, and the analysis of these products. It delineates the path from plasma products to recombinant products, and highlights products from albumin, intravenous immunoglobins, and coagulation. It offers a comprehensive review of current techniques for the analysis of proteins including electrophoresis, chromatography, spectrophotometry, and mass spectrometry as well as updates not published since 1975"--Provided by publisher.
- Subject(s)
- ISBN
- 9781439850268 (hardcover : alk. paper)
1439850267 (hardcover : alk. paper) - Bibliography Note
- Includes bibliographical references and index.
View MARC record | catkey: 9131293